| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM75641 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay |
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| EC50 | 6030±n/a nM |
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| Citation |  PubChem, PC Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56804.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1278525 |
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| Residue: | 528 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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| BDBM75641 |
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| n/a |
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| Name | BDBM75641 |
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| Synonyms: | 3-(1,3-benzodioxol-5-yl)-N'-[(E)-(6-ketocyclohexa-2,4-dien-1-ylidene)methyl]-1H-pyrazole-5-carbohydrazide | 3-(1,3-benzodioxol-5-yl)-N'-[(E)-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)methyl]-1H-pyrazole-5-carbohydrazide | 3-(1,3-benzodioxol-5-yl)-N'-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-1H-pyrazole-5-carbohydrazide | 3-(1,3-benzodioxol-5-yl)-N'-[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]-1H-pyrazole-5-carbohydrazide | 5-Benzo[1,3]dioxol-5-yl-2H-pyrazole-3-carboxylic acid [1-(2-hydroxy-phenyl)-meth-(E)-ylidene]-hydrazide | MLS000807057 | SMR000414871 | cid_16465914 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H14N4O4 |
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| Mol. Mass. | 350.3282 |
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| SMILES | Oc1ccccc1C=NNC(=O)c1cc(n[nH]1)-c1ccc2OCOc2c1 |w:8.9| |
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| Structure | 
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