| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Photoreceptor-specific nuclear receptor |
|---|
| Ligand | BDBM42930 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists |
|---|
| IC50 | 1173±n/a nM |
|---|
| Citation |  PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Photoreceptor-specific nuclear receptor |
|---|
| Name: | Photoreceptor-specific nuclear receptor |
|---|
| Synonyms: | NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 44699.83 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_401901 |
|---|
| Residue: | 410 |
|---|
| Sequence: | METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
|
|
|
|---|
| BDBM42930 |
|---|
| n/a |
|---|
| Name | BDBM42930 |
|---|
| Synonyms: | 6-(4-fluorophenyl)-3-methyl-N-(6-methyl-2-pyridinyl)-2-imidazo[2,1-b]thiazolecarboxamide | 6-(4-fluorophenyl)-3-methyl-N-(6-methyl-2-pyridyl)imidazo[2,1-b]thiazole-2-carboxamide | 6-(4-fluorophenyl)-3-methyl-N-(6-methylpyridin-2-yl)imidazo[2,1-b][1,3]thiazole-2-carboxamide | MLS000089463 | SMR000027827 | cid_3240065 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H15FN4OS |
|---|
| Mol. Mass. | 366.412 |
|---|
| SMILES | Cc1c(sc2nc(cn12)-c1ccc(F)cc1)C(=O)Nc1cccc(C)n1 |
|---|
| Structure | 
|
|---|
Search and Browse
