Ki Summary

Reaction Details

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Target

Photoreceptor-specific nuclear receptor

Ligand

BDBM75964

Substrate/Competitor

n/a

Meas. Tech.

TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists

IC50

2605±n/a nM

Citation

PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Photoreceptor-specific nuclear receptor

Name:

Photoreceptor-specific nuclear receptor

Synonyms:

NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor

Type:

PROTEIN

Mol. Mass.:

44699.83

Organism:

Homo sapiens (Human)

Description:

ChEMBL_401901

Residue:

410

Sequence:

METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN

BDBM75964

n/a

Name

BDBM75964

Synonyms:

2-[[5-(1-benzofuran-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-fluorophenyl)acetamide | 2-[[5-(1-benzofuran-2-yl)-4-methyl-1,2,4-triazol-3-yl]sulfanyl]-N-(3-fluorophenyl)ethanamide | 2-[[5-(2-benzofuranyl)-4-methyl-1,2,4-triazol-3-yl]thio]-N-(3-fluorophenyl)acetamide | 2-[[5-(benzofuran-2-yl)-4-methyl-1,2,4-triazol-3-yl]thio]-N-(3-fluorophenyl)acetamide | 2-{[5-(1-benzofuran-2-yl)-4-methyl-4H-1,2,4-triazol-3-yl]thio}-N-(3-fluorophenyl)acetamide | MLS000051255 | SMR000079256 | cid_1262637

Type

Small organic molecule

Emp. Form.

C19H15FN4O2S

Mol. Mass.

382.411

SMILES

Cn1c(SCC(=O)Nc2cccc(F)c2)nnc1-c1cc2ccccc2o1

Structure