| Reaction Details |
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 | Report a problem with these data |
| Target | Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
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| Ligand | BDBM75978 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for NR2E3 inverse agonists |
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| IC50 | 1723±n/a nM |
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| Citation |  PubChem, PC Counterscreen for NR2E3 inverse agonists: TR-FRET-based biochemical high throughput dose response assay to identify inverse agonists of the interaction between peroxisome proliferator-activated receptor gamma (PPARg) and nuclear receptor co-repressor 2 (NCOR2) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
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| Name: | Isoform 2 of Nuclear receptor corepressor 2 (TRAC-1) |
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| Synonyms: | CTG26 | NCOR2 | NCOR2_HUMAN | Nuclear receptor corepressor 2 (TRAC-1) | nuclear receptor corepressor 2 isoform 2 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 81401.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9Y618-2 gi_116256445 |
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| Residue: | 766 |
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| Sequence: | MAQRADMLRGLSPRESSLALNYAAGPRGIIDLSQVPHLPVLVPPTPGTPATAMDRLAYLP
TAPQPFSSRHSSSPLSPGGPTHLTKPTTTSSSERERDRDRERDRDREREKSILTSTTTVE
HAPIWRPGTEQSSGSSGGGGGSSSRPASHSHAHQHSPISPRTQDALQQRPSVLHNTGMKG
IITAVEPSTPTVLRSTSTSSPVRPAATFPPATHCPLGGTLDGVYPTLMEPVLLPKEAPRV
ARPERPRADTGHAFLAKPPARSGLEPASSPSKGSEPRPLVPPVSGHATIARTPAKNLAPH
HASPDPPAPPASASDPHREKTQSKPFSIQELELRSLGYHGSSYSPEGVEPVSPVSSPSLT
HDKGLPKHLEELDKSHLEGELRPKQPGPVKLGGEAAHLPHLRPLPESQPSSSPLLQTAPG
VKGHQRVVTLAQHISEVITQDYTRHHPQQLSAPLPAPLYSFPGASCPVLDLRRPPSDLYL
PPPDHGAPARGSPHSEGGKRSPEPNKTSVLGGGEDGIEPVSPPEGMTEPGHSRSAVYPLL
YRDGEQTEPSRMGSKSPGNTSQPPAFFSKLTESNSAMVKSKKQEINKKLNTHNRNEPEYN
ISQPGTEIFNMPAITGTGLMTYRSQAVQEHASTNMGLEAIIRKALMGGGGKAKVSGRPSS
RKAKSPAPGLASGDRPPSVSSVHSEGDCNRRTPLTNRVWEDRPSSAGSTPFPYNPLIMRL
QAGVMASPPPPGLPAGSGPLAGPHHAWDEEPKPLLCSQYETLSDSE
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| BDBM75978 |
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| n/a |
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| Name | BDBM75978 |
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| Synonyms: | 3-(2-ketochromen-3-yl)-N-(2-methyl-3-oxazolo[4,5-b]pyridin-2-yl-phenyl)benzamide | MLS000581554 | N-(2-methyl-3-[1,3]oxazolo[4,5-b]pyridin-2-ylphenyl)-3-(2-oxo-2H-chromen-3-yl)benzamide | N-[2-methyl-3-(2-oxazolo[4,5-b]pyridinyl)phenyl]-3-(2-oxo-1-benzopyran-3-yl)benzamide | N-[2-methyl-3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-3-(2-oxidanylidenechromen-3-yl)benzamide | N-[2-methyl-3-([1,3]oxazolo[4,5-b]pyridin-2-yl)phenyl]-3-(2-oxochromen-3-yl)benzamide | SMR000200182 | cid_2213709 |
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| Type | Small organic molecule |
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| Emp. Form. | C29H19N3O4 |
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| Mol. Mass. | 473.4789 |
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| SMILES | Cc1c(NC(=O)c2cccc(c2)-c2cc3ccccc3oc2=O)cccc1-c1nc2ncccc2o1 |
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| Structure | 
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