Reaction Details |
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Target | Large T antigen |
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Ligand | BDBM36880 |
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Substrate/Competitor | n/a |
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Meas. Tech. | A confirmatory biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to quantify activity of synthesized compounds that inhibit the ATPase activity of Tag (3) |
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IC50 | 35700±n/a nM |
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Citation | PubChem, PC A confirmatory biochemical assay using the ADP-Hunter methodology, purified TAg, and ATP to quantify activity of synthesized compounds that inhibit the ATPase activity of Tag (3) PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Large T antigen |
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Name: | Large T antigen |
Synonyms: | LT | LT-AG | LT_SV40 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 81575.54 |
Organism: | Simian virus 40 |
Description: | P03070 |
Residue: | 708 |
Sequence: | MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK
KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS
QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS
VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP
FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE
MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM
LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR
YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG
ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEFSVPKTLQAR
FVKQIDFRAKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK
ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE
TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
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BDBM36880 |
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n/a |
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Name | BDBM36880 |
Synonyms: | 2,2'-THIOBIS(4,6-DICHLOROPHENOL) | 2,4-dichloro-6-(3,5-dichloro-2-hydroxyphenyl)sulfanylphenol | 2,4-dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)thio]phenol | 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)thio]phenol | 2-[3,5-bis(chloranyl)-2-oxidanyl-phenyl]sulfanyl-4,6-bis(chloranyl)phenol | Bithionol | HL-3 | MLS000028403 | SMR000058374 | cid_2406 |
Type | Small organic molecule |
Emp. Form. | C12H6Cl4O2S |
Mol. Mass. | 356.052 |
SMILES | Oc1c(Cl)cc(Cl)cc1Sc1cc(Cl)cc(Cl)c1O |
Structure |
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