| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase 1 |
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| Ligand | BDBM76173 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay |
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| IC50 | 2170±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase 1 |
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| Name: | Intestinal-type alkaline phosphatase 1 |
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| Synonyms: | Alpi | PPBI1_RAT |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 58396.39 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P15693 |
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| Residue: | 540 |
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| Sequence: | MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
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| BDBM76173 |
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| n/a |
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| Name | BDBM76173 |
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| Synonyms: | 1-(3,5-Dimethyl-phenyl)-3-(9-thiophen-2-ylmethyl-9-aza-bicyclo[3.3.1]non-3-yl)-thiourea | 1-(3,5-dimethylphenyl)-3-[9-(2-thenyl)-9-azabicyclo[3.3.1]nonan-3-yl]thiourea | 1-(3,5-dimethylphenyl)-3-[9-(thiophen-2-ylmethyl)-9-azabicyclo[3.3.1]nonan-3-yl]thiourea | MLS000549793 | SMR000173334 | cid_3218185 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H29N3S2 |
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| Mol. Mass. | 399.616 |
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| SMILES | [H]C12CCCC([H])(CC(C1)NC(=S)Nc1cc(C)cc(C)c1)N2Cc1cccs1 |
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| Structure | 
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