| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM75739 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay - Set 2 |
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| IC50 | 15500±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of human intestinal alkaline phosphatase via a luminescent assay - Set 2 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56804.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1278525 |
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| Residue: | 528 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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| BDBM75739 |
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| n/a |
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| Name | BDBM75739 |
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| Synonyms: | (1Z)-1-[(4-hydroxyphenyl)hydrazinylidene]-2-naphthalenone | (1Z)-1-[(4-hydroxyphenyl)hydrazinylidene]naphthalen-2-one | (1Z)-1-[(4-hydroxyphenyl)hydrazono]naphthalen-2-one | 1-[(4-hydroxyphenyl)diazenyl]-2-naphthol | MLS000578050 | SMR000186261 | cid_9566592 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H12N2O2 |
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| Mol. Mass. | 264.2787 |
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| SMILES | Oc1ccc(cc1)N=Nc1c(O)ccc2ccccc12 |w:8.9| |
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| Structure | 
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