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TargetIntestinal-type alkaline phosphatase
LigandBDBM75656
Substrate/Competitorn/a
Meas. Tech.Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay - Set 2
EC50 8770±n/a nM
Citation PubChem, PC Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay - Set 2 PubChem Bioassay(2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Intestinal-type alkaline phosphatase
Name:Intestinal-type alkaline phosphatase
Synonyms:ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN
Type:PROTEIN
Mol. Mass.:56804.94
Organism:Homo sapiens (Human)
Description:ChEMBL_1278525
Residue:528
Sequence:
MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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  Blast E-value cutoff:
BDBM75656
n/a
NameBDBM75656
Synonyms:(3Z)-5-(hydroxyamino)-6-nitroso-3-phenacylidene-1,4-dihydropyrazin-2-one | (3Z)-6-nitroso-5-(oxidanylamino)-3-phenacylidene-1,4-dihydropyrazin-2-one | MLS001164264 | SMR000539633 | cid_5904198
TypeSmall organic molecule
Emp. Form.C12H10N4O4
Mol. Mass.274.2322
SMILESONc1nc(CC(=O)c2ccccc2)c(=O)[nH]c1N=O
Structure
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