Ki Summary

Reaction Details

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Target

Alkaline phosphatase, tissue-nonspecific isozyme

Ligand

BDBM50242280

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of uHTS inhibitors of Human Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase.

IC50

>100000±n/a nM

Citation

PubChem, PC Dose Response confirmation of uHTS inhibitors of Human Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase. PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Alkaline phosphatase, tissue-nonspecific isozyme

Name:

Alkaline phosphatase, tissue-nonspecific isozyme

Synonyms:

ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor

Type:

PROTEIN

Mol. Mass.:

57306.17

Organism:

Homo sapiens (Human)

Description:

ChEMBL_1448917

Residue:

524

Sequence:

MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGD
GMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCG
VKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAH
SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDE
KARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELN
RNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIG
QAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPG
YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYV
PHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF

BDBM50242280

n/a

Name

BDBM50242280

Synonyms:

(2S,3S,4S,5R,6S)-6-(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yloxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid | CHEMBL520546 | Quercetin 3-O-beta-D-glucuronide | Quercetin-3-O-beta-D-glucuronopyranoside | cid_12004528 | quercetin glucuronide

Type

Small organic molecule

Emp. Form.

C21H18O13

Mol. Mass.

478.3598

SMILES

O[C@H]1[C@H](Oc2c(O)c3c(cc(O)cc3=O)oc2-c2ccc(O)c(O)c2)O[C@@H]([C@@H](O)[C@@H]1O)C(O)=O |r|

Structure