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Targettyrosine-protein phosphatase non-receptor type 12 isoform 2
LigandBDBM46272
Substrate/Competitorn/a
Meas. Tech.SAR Selectivity Analysis of small molecule inhibitors of PEST using pCAP in a fluorescence assay
IC50 7600±n/a nM
Citation PubChem PC SAR Selectivity Analysis of small molecule inhibitors of PEST using pCAP in a fluorescence assay PubChem Bioassay (2010)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
tyrosine-protein phosphatase non-receptor type 12 isoform 2
Name:DNMT3A2/3L complex
Synonyms:DNA (cytosine-5)-methyltransferase 3A | DNA MTase HsaIIIA | DNA methyltransferase HsaIIIA | Dnmt3a | M.HsaIIIA
Type:PROTEIN
Mol. Mass.:101857.24
Organism:Homo sapiens (Human)
Description:ChEMBL_1510405
Residue:912
Sequence:
MPAMPSSGPGDTSSSAAEREEDRKDGEEQEEPRGKEERQEPSTTARKVGRPGRKRKHPPV
ESGDTPKDPAVISKSPSMAQDSGASELLPNGDLEKRSEPQPEEGSPAGGQKGGAPAEGEG
AAETLPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSL
RQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVE
EASPPAVQQPTDPASPTVATTPEPVGSDAGDKNATKAGDDEPEYEDGRGFGIGELVWGKL
RGFSWWPGRIVSWWMTGRSRAAEGTRWVMWFGDGKFSVVCVEKLMPLSSFCSAFHQATYN
KQPMYRKAIYEVLQVASSRAGKLFPVCHDSDESDTAKAVEVQNKPMIEWALGGFQPSGPK
GLEPPEEEKNPYKEVYTDMWVEPEAAAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLV
YEVRQKCRNIEDICISCGSLNVTLEHPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTIC
CGGREVLMCGNNNCCRCFCVECVDLLVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRRED
WPSRLQMFFANNHDQEFDPPKVYPPVPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRY
IASEVCEDSITVGMVRHQGKIMYVGDVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPAR
KGLYEGTGRLFFEFYRLLHDARPKEGDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMI
DAKEVSAAHRARYFWGNLPGMNRPLASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSI
KQGKDQHFPVFMNEKEDILWCTEMERVFGFPVHYTDVSNMSRLARQRLLGRSWSVPVIRH
LFAPLKEYFACV
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  Blast E-value cutoff:
BDBM46272
n/a
NameBDBM46272
Synonyms:2-[2-ethoxy-6-iodanyl-4-[(E)-(4-oxidanylidene-2-phenylazanyl-1,3-thiazol-5-ylidene)methyl]phenoxy]ethanoic acid | 2-[4-[(E)-(2-anilino-4-keto-2-thiazolin-5-ylidene)methyl]-2-ethoxy-6-iodo-phenoxy]acetic acid | 2-[4-[(E)-(2-anilino-4-oxo-1,3-thiazol-5-ylidene)methyl]-2-ethoxy-6-iodophenoxy]acetic acid | 2-[4-[(E)-(2-anilino-4-oxo-5-thiazolylidene)methyl]-2-ethoxy-6-iodophenoxy]acetic acid | MLS-0425587.0001 | cid_1756795
TypeSmall organic molecule
Emp. Form.C20H17IN2O5S
Mol. Mass.524.329
SMILESCCOc1cc(C=C2SC(Nc3ccccc3)=NC2=O)cc(I)c1OCC(O)=O |w:6.5,c:17|
Structure
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