| Reaction Details |
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 | Report a problem with these data |
| Target | Protein-arginine deiminase type-4 |
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| Ligand | BDBM70488 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical dose response assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) |
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| IC50 | 42000±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical dose response assay to identify inhibitors of Protein Arginine Deiminase 4 (PAD4) PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Protein-arginine deiminase type-4 |
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| Name: | Protein-arginine deiminase type-4 |
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| Synonyms: | PAD4 | PADI4 | PADI4_HUMAN | PADI5 | PDI5 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 74078.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_216548487 |
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| Residue: | 663 |
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| Sequence: | MAQGTLIRVTPEQPTHAVCVLGTLTQLDICSSAPEDCTSFSINASPGVVVDIAHGPPAKK
KSTGSSTWPLDPGVEVTLTMKVASGSTGDQKVQISYYGPKTPPVKALLYLTGVEISLCAD
ITRTGKVKPTRAVKDQRTWTWGPCGQGAILLVNCDRDNLESSAMDCEDDEVLDSEDLQDM
SLMTLSTKTPKDFFTNHTLVLHVARSEMDKVRVFQATRGKLSSKCSVVLGPKWPSHYLMV
PGGKHNMDFYVEALAFPDTDFPGLITLTISLLDTSNLELPEAVVFQDSVVFRVAPWIMTP
NTQPPQEVYACSIFENEDFLKSVTTLAMKAKCKLTICPEEENMDDQWMQDEMEIGYIQAP
HKTLPVVFDSPRNRGLKEFPIKRVMGPDFGYVTRGPQTGGISGLDSFGNLEVSPPVTVRG
KEYPLGRILFGDSCYPSNDSRQMHQALQDFLSAQQVQAPVKLYSDWLSVGHVDEFLSFVP
APDRKGFRLLLASPRSCYKLFQEQQNEGHGEALLFEGIKKKKQQKIKNILSNKTLREHNS
FVERCIDWNRELLKRELGLAESDIIDIPQLFKLKEFSKAEAFFPNMVNMLVLGKHLGIPK
PFGPVINGRCCLEEKVCSLLEPLGLQCTFINDFFTYHIRHGEVHCGTNVRRKPFSFKWWN
MVP
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| BDBM70488 |
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| n/a |
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| Name | BDBM70488 |
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| Synonyms: | (3Z)-3-[hydroxy(methoxy)methylene]isoquinoline-1,4-quinone | (3Z)-3-[hydroxy(methoxy)methylidene]isoquinoline-1,4-dione | (3Z)-3-[methoxy(oxidanyl)methylidene]isoquinoline-1,4-dione | MLS000549933 | SMR000113373 | cid_6093506 | methyl 4-hydroxy-1-oxo-1,2-dihydro-3-isoquinolinecarboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C11H9NO4 |
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| Mol. Mass. | 219.1935 |
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| SMILES | COC(=O)c1[nH]c(=O)c2ccccc2c1O |
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| Structure | 
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