| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM10 |
|---|
| Ligand | BDBM78434 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay |
|---|
| IC50 | 29100±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mitochondrial import inner membrane translocase subunit TIM10 |
|---|
| Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
|---|
| Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 10303.50 |
|---|
| Organism: | Saccharomyces cerevisiae S288c |
|---|
| Description: | gi_285809906 |
|---|
| Residue: | 93 |
|---|
| Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
|
|
|
|---|
| BDBM78434 |
|---|
| n/a |
|---|
| Name | BDBM78434 |
|---|
| Synonyms: | 2-chloranyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid | 2-chloro-10-[3-(4-methyl-1-piperazinyl)propyl]phenothiazine;ethane-1,2-disulfonic acid | 2-chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine;ethane-1,2-disulfonic acid | 2-chloro-10-[3-(4-methylpiperazino)propyl]phenothiazine;ethane-1,2-disulfonic acid | Compazine | Compro | MLS001148133 | PROCHLORPERAZINE | SMR000653454 | cid_91499 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H24ClN3S |
|---|
| Mol. Mass. | 373.943 |
|---|
| SMILES | CN1CCN(CCCN2c3ccccc3Sc3ccc(Cl)cc23)CC1 |
|---|
| Structure | 
|
|---|
Search and Browse
