Reaction Details |
| Report a problem with these data |
Target | Ubiquitin-conjugating enzyme E2 N |
---|
Ligand | BDBM78619 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay |
---|
IC50 | 965±73 nM |
---|
Citation | PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Ubiquitin-conjugating enzyme E2 N |
---|
Name: | Ubiquitin-conjugating enzyme E2 N |
Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
Type: | PROTEIN |
Mol. Mass.: | 17137.61 |
Organism: | Homo sapiens (Human) |
Description: | EBI_101440 |
Residue: | 152 |
Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
|
|
|
BDBM78619 |
---|
n/a |
---|
Name | BDBM78619 |
Synonyms: | 2-amino-N'-(2,3-dimethoxybenzylidene)-4-methyl-1,3-thiazole-5-carbohydrazide | 2-amino-N-[(2,3-dimethoxybenzylidene)amino]-4-methyl-thiazole-5-carboxamide | 2-amino-N-[(2,3-dimethoxyphenyl)methylideneamino]-4-methyl-1,3-thiazole-5-carboxamide | 2-amino-N-[(2,3-dimethoxyphenyl)methylideneamino]-4-methyl-5-thiazolecarboxamide | 2-azanyl-N-[(2,3-dimethoxyphenyl)methylideneamino]-4-methyl-1,3-thiazole-5-carboxamide | MLS000545717 | SMR000162968 | cid_729197 |
Type | Small organic molecule |
Emp. Form. | C14H16N4O3S |
Mol. Mass. | 320.367 |
SMILES | COc1cccc(C=NNC(=O)c2sc(N)nc2C)c1OC |
Structure |
|