| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin-conjugating enzyme E2 N |
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| Ligand | BDBM78633 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
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| IC50 | 548±17 nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ubiquitin-conjugating enzyme E2 N |
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| Name: | Ubiquitin-conjugating enzyme E2 N |
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| Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 17137.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101440 |
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| Residue: | 152 |
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| Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
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| BDBM78633 |
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| n/a |
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| Name | BDBM78633 |
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| Synonyms: | 2-amino-4-methyl-N-(veratrylideneamino)thiazole-5-carboxamide | 2-amino-N'-(3,4-dimethoxybenzylidene)-4-methyl-1,3-thiazole-5-carbohydrazide | 2-amino-N-[(3,4-dimethoxyphenyl)methylideneamino]-4-methyl-1,3-thiazole-5-carboxamide | 2-amino-N-[(3,4-dimethoxyphenyl)methylideneamino]-4-methyl-5-thiazolecarboxamide | 2-azanyl-N-[(3,4-dimethoxyphenyl)methylideneamino]-4-methyl-1,3-thiazole-5-carboxamide | MLS000545626 | SMR000162970 | cid_729219 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H16N4O3S |
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| Mol. Mass. | 320.367 |
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| SMILES | COc1ccc(C=NNC(=O)c2sc(N)nc2C)cc1OC |
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| Structure | 
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