| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin-conjugating enzyme E2 N |
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| Ligand | BDBM65651 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
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| IC50 | 1351±80 nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ubiquitin-conjugating enzyme E2 N |
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| Name: | Ubiquitin-conjugating enzyme E2 N |
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| Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 17137.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101440 |
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| Residue: | 152 |
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| Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
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| BDBM65651 |
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| n/a |
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| Name | BDBM65651 |
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| Synonyms: | 4-[(Z)-[4-(4-chlorobenzyl)-3-keto-1,4-benzoxazin-2-ylidene]methyl]-N-[3-(4-methylpiperazino)propyl]benzamide | 4-[(Z)-[4-[(4-chlorophenyl)methyl]-3-oxidanylidene-1,4-benzoxazin-2-ylidene]methyl]-N-[3-(4-methylpiperazin-1-yl)propyl]benzamide | 4-[(Z)-[4-[(4-chlorophenyl)methyl]-3-oxo-1,4-benzoxazin-2-ylidene]methyl]-N-[3-(4-methyl-1-piperazinyl)propyl]benzamide | 4-[(Z)-[4-[(4-chlorophenyl)methyl]-3-oxo-1,4-benzoxazin-2-ylidene]methyl]-N-[3-(4-methylpiperazin-1-yl)propyl]benzamide | MLS001030809 | SMR000635124 | cid_24792840 |
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| Type | Small organic molecule |
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| Emp. Form. | C31H33ClN4O3 |
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| Mol. Mass. | 545.072 |
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| SMILES | CN1CCN(CCCNC(=O)c2ccc(\C=C3/Oc4ccccc4N(Cc4ccc(Cl)cc4)C3=O)cc2)CC1 |
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| Structure | 
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