Reaction Details |
| Report a problem with these data |
Target | Mitochondrial import inner membrane translocase subunit TIM23 |
---|
Ligand | BDBM34233 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. |
---|
IC50 | 880±n/a nM |
---|
Citation | PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. PubChem Bioassay(2011)[AID] |
---|
More Info.: | Get all data from this article, Solution Info, Assay Method |
---|
|
Mitochondrial import inner membrane translocase subunit TIM23 |
---|
Name: | Mitochondrial import inner membrane translocase subunit TIM23 |
Synonyms: | MAS6 | MIM23 | MPI3 | TIM23 | TIM23_YEAST | TPA: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex) |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 23245.32 |
Organism: | Saccharomyces cerevisiae S288c |
Description: | gi_285814664 |
Residue: | 222 |
Sequence: | MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHP
LAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQG
LQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIG
AGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK
|
|
|
BDBM34233 |
---|
n/a |
---|
Name | BDBM34233 |
Synonyms: | 2-Phenyl-benzo[d]isoselenazol-3-one | 2-Phenyl-benzo[d]isoselenazol-3-one(Ebselen) | 2-phenyl-1,2-benzisoselazol-3(2H)-one | 2-phenyl-1,2-benzoselenazol-3-one | 2-phenylbenzo[d][1,2]selenazol-3(2H)-one | CHEMBL51085 | EBSELEN | Ebselen (C5) | MLS000028488 | SMR000058445 | cid_3194 | med.21724, Compound 153 |
Type | Small organic molecule |
Emp. Form. | C13H9NOSe |
Mol. Mass. | 274.18 |
SMILES | O=c1n([se]c2ccccc12)-c1ccccc1 |
Structure |
|