| Reaction Details |
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 | Report a problem with these data |
| Target | BRCA1-associated RING domain protein 1 |
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| Ligand | BDBM79632 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay |
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| IC50 | 3890±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of Inhibitors of Mdm2/MdmX interaction using a Brca1/Bard1 BiLC Counterscreen assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| BRCA1-associated RING domain protein 1 |
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| Name: | BRCA1-associated RING domain protein 1 |
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| Synonyms: | BARD-1 | BARD1 | BARD1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 86678.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_116241265 |
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| Residue: | 777 |
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| Sequence: | MPDNRQPRNRQPRIRSGNEPRSAPAMEPDGRGAWAHSRAALDRLEKLLRCSRCTNILREP
VCLGGCEHIFCSNCVSDCIGTGCPVCYTPAWIQDLKINRQLDSMIQLCSKLRNLLHDNEL
SDLKEDKPRKSLFNDAGNKKNSIKMWFSPRSKKVRYVVSKASVQTQPAIKKDASAQQDSY
EFVSPSPPADVSERAKKASARSGKKQKKKTLAEINQKWNLEAEKEDGEFDSKEESKQKLV
SFCSQPSVISSPQINGEIDLLASGSLTESECFGSLTEVSLPLAEQIESPDTKSRNEVVTP
EKVCKNYLTSKKSLPLENNGKRGHHNRLSSPISKRCRTSILSTSGDFVKQTVPSENIPLP
ECSSPPSCKRKVGGTSGRKNSNMSDEFISLSPGTPPSTLSSSSYRRVMSSPSAMKLLPNM
AVKRNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELL
LQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPVDYTDDESMK
SLLLLPEKNESSSASHCSVMNTGQRRDGPLVLIGSGLSSEQQKMLSELAVILKAKKYTEF
DSTVTHVVVPGDAVQSTLKCMLGILNGCWILKFEWVKACLRRKVCEQEEKYEIPEGPRRS
RLNREQLLPKLFDGCYFYLWGTFKHHPKDNLIKLVTAGGGQILSRKPKPDSDVTQTINTV
AYHARPDSDQRFCTQYIIYEDLCNYHPERVRQGKVWKAPSSWFIDCVMSFELLPLDS
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| BDBM79632 |
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| n/a |
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| Name | BDBM79632 |
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| Synonyms: | 2-hydroxy-6-isopropyl-cyclohepta-2,4,6-trien-1-one | 2-hydroxy-6-propan-2-yl-1-cyclohepta-2,4,6-trienone | 2-hydroxy-6-propan-2-ylcyclohepta-2,4,6-trien-1-one | 2-oxidanyl-6-propan-2-yl-cyclohepta-2,4,6-trien-1-one | MLS001048906 | SMR000387099 | US9790158, 9 | cid_3611 |
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| Type | Small organic molecule |
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| Emp. Form. | C10H12O2 |
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| Mol. Mass. | 164.2011 |
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| SMILES | CC(C)c1cccc(O)c(=O)c1 |
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| Structure | 
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