BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBcl-2-related protein A1
LigandBDBM29615
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen
IC50 1100±24 nM
Citation PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Bcl-2-related protein A1
Name:Bcl-2-related protein A1
Synonyms:A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1
Type:Apoptosis regulator protein
Mol. Mass.:19909.74
Organism:Mus musculus (Mouse)
Description:gi_11024684
Residue:172
Sequence:
MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM29615
n/a
NameBDBM29615
Synonyms:6-methoxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid | MLS000072167 | SMR000009698 | US11584714, Compound 15 | cid_652912
TypeSmall organic molecule
Emp. Form.C14H15NO3
Mol. Mass.245.2738
SMILESCOc1cccc2C3C=CCC3C(Nc12)C(O)=O |c:8|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: