| Reaction Details |
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 | Report a problem with these data |
| Target | Bcl-2-related protein A1 |
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| Ligand | BDBM51914 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen |
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| IC50 | 550±40 nM |
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| Citation |  PubChem, PC Dose Response confirmation of UBC13 Polyubiquitin Inhibitors using a Bfl-1 counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Bcl-2-related protein A1 |
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| Name: | Bcl-2-related protein A1 |
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| Synonyms: | A1 | A1-A | B-cell leukemia/lymphoma 2 related protein A1a | B2LA1_MOUSE | Bcl2a1 | Bcl2a1a | Bfl-1 | Bfl1 | Hemopoietic-specific early response protein | Protein BFL-1 |
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| Type: | Apoptosis regulator protein |
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| Mol. Mass.: | 19909.74 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | gi_11024684 |
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| Residue: | 172 |
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| Sequence: | MAESELMHIHSLAEHYLQYVLQVPAFESAPSQACRVLQRVAFSVQKEVEKNLKSYLDDFH
VESIDTARIIFNQVMEKEFEDGIINWGRIVTIFAFGGVLLKKLPQEQIALDVCAYKQVSS
FVAEFIMNNTGEWIRQNGGWEDGFIKKFEPKSGWLTFLQMTGQIWEMLFLLK
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| BDBM51914 |
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| n/a |
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| Name | BDBM51914 |
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| Synonyms: | 2-(diethylamino)ethyl 4-[[(Z)-2-cyano-2-[4-(2-oxidanylidenechromen-3-yl)-1,3-thiazol-2-yl]ethenyl]amino]benzoate | 2-(diethylamino)ethyl 4-[[(Z)-2-cyano-2-[4-(2-oxochromen-3-yl)-1,3-thiazol-2-yl]ethenyl]amino]benzoate | 4-[[(Z)-2-cyano-2-[4-(2-ketochromen-3-yl)thiazol-2-yl]vinyl]amino]benzoic acid 2-(diethylamino)ethyl ester | 4-[[(Z)-2-cyano-2-[4-(2-oxo-1-benzopyran-3-yl)-2-thiazolyl]ethenyl]amino]benzoic acid 2-(diethylamino)ethyl ester | MLS001164950 | SMR000540247 | cid_1837712 |
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| Type | Small organic molecule |
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| Emp. Form. | C28H26N4O4S |
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| Mol. Mass. | 514.595 |
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| SMILES | CCN(CC)CCOC(=O)c1ccc(cc1)N=CC(C#N)c1nc(cs1)-c1cc2ccccc2oc1=O |w:16.16| |
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| Structure | 
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