| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM50322732 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | >71542±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Tropomyosin alpha-1 chain |
|---|
| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
|
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|
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| BDBM50322732 |
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| n/a |
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| Name | BDBM50322732 |
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| Synonyms: | 2-(5-methylisoxazol-3-ylamino)-2-oxoethyl 2-(furan-2-carboxamido)-3-phenylpropanoate | CHEMBL1172020 | cid_3000182 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19N3O6 |
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| Mol. Mass. | 397.3814 |
|---|
| SMILES | Cc1cc(NC(=O)COC(=O)C(Cc2ccccc2)NC(=O)c2ccco2)no1 |
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| Structure | 
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