Ki Summary

Reaction Details

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Target

Tropomyosin alpha-1 chain

Ligand

BDBM79646

Substrate/Competitor

n/a

Meas. Tech.

Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)

EC50

>2648±n/a nM

Citation

PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Tropomyosin alpha-1 chain

Name:

Tropomyosin alpha-1 chain

Synonyms:

TPM1 | TPM1_PIG | cardiac alpha tropomyosin

Type:

Enzyme Catalytic Domain

Mol. Mass.:

32681.01

Organism:

Sus scrofa

Description:

P42639

Residue:

284

Sequence:

MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI

BDBM79646

n/a

Name

BDBM79646

Synonyms:

6-fluoranyl-4-oxidanidyl-7-pyrrolidin-1-yl-2,3-dihydro-1H-cyclopenta[b]quinoxalin-9-ium 9-oxide | 6-fluoro-4-oxido-7-(1-pyrrolidinyl)-2,3-dihydro-1H-cyclopenta[b]quinoxalin-9-ium 9-oxide | 6-fluoro-4-oxido-7-pyrrolidin-1-yl-2,3-dihydro-1H-cyclopenta[b]quinoxalin-9-ium 9-oxide | 6-fluoro-4-oxido-7-pyrrolidino-2,3-dihydro-1H-cyclopenta[b]quinoxalin-9-ium 9-oxide | 6-fluoro-7-pyrrolidin-1-yl-2,3-dihydro-1H-cyclopenta[b]quinoxaline 4,9-dioxide | MLS000045751 | SMR000027708 | cid_3242663

Type

Small organic molecule

Emp. Form.

C15H16FN3O2

Mol. Mass.

289.3048

SMILES

[O-]N1C2=C(CCC2)[N+](=O)c2cc(N3CCCC3)c(F)cc12 |t:2|

Structure