| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM50881 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | 190.67±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM50881 |
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| n/a |
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| Name | BDBM50881 |
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| Synonyms: | 3-(2-chlorophenyl)-6-[4-(diethylamino)benzylidene][1,3]thiazolo[2,3-c][1,2,4]triazol-5(6H)-one | 3-(2-chlorophenyl)-6-[4-(diethylamino)benzylidene]thiazolo[2,3-c][1,2,4]triazol-5-one | 3-(2-chlorophenyl)-6-[[4-(diethylamino)phenyl]methylidene]-5-thiazolo[2,3-c][1,2,4]triazolone | 3-(2-chlorophenyl)-6-[[4-(diethylamino)phenyl]methylidene]-[1,3]thiazolo[2,3-c][1,2,4]triazol-5-one | MLS000535086 | SMR000142570 | cid_2936930 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H19ClN4OS |
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| Mol. Mass. | 410.92 |
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| SMILES | CCN(CC)c1ccc(C=c2sc3nnc(-c4ccccc4Cl)n3c2=O)cc1 |
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| Structure | 
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