| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM79709 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | 1548±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM79709 |
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| n/a |
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| Name | BDBM79709 |
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| Synonyms: | (5Z)-1,3-dimethyl-5-(3-methyl-4-pyrrolidino-benzylidene)-2-thioxo-4-imidazolidinone | (5Z)-1,3-dimethyl-5-[(3-methyl-4-pyrrolidin-1-yl-phenyl)methylidene]-2-sulfanylidene-imidazolidin-4-one | (5Z)-1,3-dimethyl-5-[(3-methyl-4-pyrrolidin-1-ylphenyl)methylidene]-2-sulfanylideneimidazolidin-4-one | (5Z)-1,3-dimethyl-5-[[3-methyl-4-(1-pyrrolidinyl)phenyl]methylidene]-2-sulfanylidene-4-imidazolidinone | 1,3-dimethyl-5-[3-methyl-4-(1-pyrrolidinyl)benzylidene]-2-thioxo-4-imidazolidinone | MLS000663843 | SMR000292355 | cid_891056 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H21N3OS |
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| Mol. Mass. | 315.433 |
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| SMILES | CN1C(=S)N(C)\C(=C/c2ccc(N3CCCC3)c(C)c2)C1=O |
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| Structure | 
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