| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM79710 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | 565.38±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM79710 |
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| n/a |
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| Name | BDBM79710 |
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| Synonyms: | MLS000335382 | N-aminocarbonyl-2-[2-(3,3-dimethyl-2-oxidanylidene-butylidene)-5-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-4-oxidanylidene-1,3-thiazolidin-3-yl]ethanamide | N-carbamoyl-2-[2-(3,3-dimethyl-2-oxobutylidene)-5-[[5-(4-nitrophenyl)-2-furanyl]methylidene]-4-oxo-3-thiazolidinyl]acetamide | N-carbamoyl-2-[2-(3,3-dimethyl-2-oxobutylidene)-5-[[5-(4-nitrophenyl)furan-2-yl]methylidene]-4-oxo-1,3-thiazolidin-3-yl]acetamide | N-carbamoyl-2-[4-keto-2-(2-keto-3,3-dimethyl-butylidene)-5-[[5-(4-nitrophenyl)-2-furyl]methylene]thiazolidin-3-yl]acetamide | SMR000250131 | cid_3565302 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H22N4O7S |
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| Mol. Mass. | 498.508 |
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| SMILES | CC(C)(C)C(=O)\C=c1/s\c(=C/c2ccc(o2)-c2ccc(cc2)[N+]([O-])=O)c(=O)n1CC(=O)NC(N)=O |
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| Structure | 
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