| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM65365 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | 1577±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM65365 |
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| n/a |
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| Name | BDBM65365 |
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| Synonyms: | (Z)-2-cyano-N-(4-methoxyphenyl)-3-(5-morpholin-4-ylfuran-2-yl)prop-2-enamide | (Z)-2-cyano-N-(4-methoxyphenyl)-3-(5-morpholino-2-furyl)acrylamide | (Z)-2-cyano-N-(4-methoxyphenyl)-3-[5-(4-morpholinyl)-2-furanyl]-2-propenamide | MLS000712042 | SMR000281809 | cid_1922517 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H19N3O4 |
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| Mol. Mass. | 353.3719 |
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| SMILES | COc1ccc(NC(=O)C(=C/c2ccc(o2)N2CCOCC2)\C#N)cc1 |
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| Structure | 
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