| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3G |
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| Ligand | BDBM80160 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 2440±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA dC->dU-editing enzyme APOBEC-3G |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3G |
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| Synonyms: | ABC3G_HUMAN | APOBEC3G |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46419.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13399304 |
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| Residue: | 384 |
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| Sequence: | MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN
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| BDBM80160 |
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| n/a |
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| Name | BDBM80160 |
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| Synonyms: | 3-(5-methyl-1H-pyrazol-3-yl)-4-[(3-methyl-2-thienyl)methyleneamino]-1H-1,2,4-triazole-5-thione | 3-(5-methyl-1H-pyrazol-3-yl)-4-[(3-methyl-2-thiophenyl)methylideneamino]-1H-1,2,4-triazole-5-thione | 3-(5-methyl-1H-pyrazol-3-yl)-4-[(3-methylthiophen-2-yl)methylideneamino]-1H-1,2,4-triazole-5-thione | 5-(5-Methyl-2H-pyrazol-3-yl)-4-{[1-(3-methyl-thiophen-2-yl)-meth-(E)-ylidene]-amino}-4H-[1,2,4]triazole-3-thiol | MLS000331369 | SMR000220901 | cid_1400197 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H12N6S2 |
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| Mol. Mass. | 304.394 |
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| SMILES | Cc1cc(n[nH]1)-c1n[nH]c(=S)n1N=Cc1sccc1C |w:12.13| |
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| Structure | 
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