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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | DNA dC->dU-editing enzyme APOBEC-3G | ||
| Ligand | BDBM80165 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay | ||
| Temperature | 298.15±n/a K | ||
| IC50 | 2480±n/a nM | ||
| Comments | extracted | ||
| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| DNA dC->dU-editing enzyme APOBEC-3G | |||
| Name: | DNA dC->dU-editing enzyme APOBEC-3G | ||
| Synonyms: | ABC3G_HUMAN | APOBEC3G | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 46419.54 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_13399304 | ||
| Residue: | 384 | ||
| Sequence: |
| ||
| BDBM80165 | |||
| n/a | |||
| Name | BDBM80165 | ||
| Synonyms: | (6E)-2-methoxy-6-[[[3-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-5-thioxo-1H-1,2,4-triazol-4-yl]amino]methylene]cyclohexa-2,4-dien-1-one | (6E)-2-methoxy-6-[[[5-sulfanylidene-3-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-1H-1,2,4-triazol-4-yl]amino]methylidene]-1-cyclohexa-2,4-dienone | (6E)-2-methoxy-6-[[[5-sulfanylidene-3-(1,4,5,6-tetrahydrocyclopenta[c]pyrazol-3-yl)-1H-1,2,4-triazol-4-yl]amino]methylidene]cyclohexa-2,4-dien-1-one | 2-{[(E)-3-Mercapto-5-(1,4,5,6-tetrahydro-cyclopentapyrazol-3-yl)-[1,2,4]triazol-4-ylimino]-methyl}-6-methoxy-phenol | MLS000331418 | SMR000220897 | cid_6415306 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H16N6O2S | ||
| Mol. Mass. | 356.402 | ||
| SMILES | COc1cccc(C=Nn2c(n[nH]c2=S)-c2n[nH]c3CCCc23)c1O |w:8.8| | ||
| Structure | 
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