| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
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| Ligand | BDBM80457 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 1240±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
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| BDBM80457 |
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| n/a |
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| Name | BDBM80457 |
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| Synonyms: | 2-[(4Z)-4-[(1-ethyl-2,5-dimethyl-3-pyrrolyl)methylidene]-2,5-dioxo-1-imidazolidinyl]-N-(4-fluorophenyl)acetamide | 2-[(4Z)-4-[(1-ethyl-2,5-dimethyl-pyrrol-3-yl)methylene]-2,5-diketo-imidazolidin-1-yl]-N-(4-fluorophenyl)acetamide | 2-[(4Z)-4-[(1-ethyl-2,5-dimethyl-pyrrol-3-yl)methylidene]-2,5-bis(oxidanylidene)imidazolidin-1-yl]-N-(4-fluorophenyl)ethanamide | 2-[(4Z)-4-[(1-ethyl-2,5-dimethylpyrrol-3-yl)methylidene]-2,5-dioxoimidazolidin-1-yl]-N-(4-fluorophenyl)acetamide | 2-{4-[(1-ethyl-2,5-dimethyl-1H-pyrrol-3-yl)methylene]-2,5-dioxo-1-imidazolidinyl}-N-(4-fluorophenyl)acetamide | MLS000697981 | SMR000226517 | cid_6294434 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H21FN4O3 |
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| Mol. Mass. | 384.4041 |
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| SMILES | CCn1c(C)cc(\C=C2/NC(=O)N(CC(=O)Nc3ccc(F)cc3)C2=O)c1C |
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| Structure | 
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