Ki Summary

Reaction Details

Report a problem with these data

Target

DNA dC->dU-editing enzyme APOBEC-3A

Ligand

BDBM80458

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay

Temperature

298.15±n/a K

IC50

1140±n/a nM

Comments

extracted

Citation

PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

DNA dC->dU-editing enzyme APOBEC-3A

Name:

DNA dC->dU-editing enzyme APOBEC-3A

Synonyms:

ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A

Type:

Enzyme Catalytic Domain

Mol. Mass.:

23013.77

Organism:

Homo sapiens (Human)

Description:

gi_21955158

Residue:

199

Sequence:

MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN

BDBM80458

n/a

Name

BDBM80458

Synonyms:

(1E,2E)-3-(2-nitrophenyl)acrylaldehyde (4,6-dipiperidin-1-yl-1,3,5-triazin-2-yl)hydrazone | (4,6-dipiperidino-s-triazin-2-yl)-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]amine | MLS000723636 | N-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]-4,6-bis(1-piperidinyl)-1,3,5-triazin-2-amine | N-[[(E)-3-(2-nitrophenyl)prop-2-enylidene]amino]-4,6-di(piperidin-1-yl)-1,3,5-triazin-2-amine | SMR000305231 | cid_16189284

Type

Small organic molecule

Emp. Form.

C22H28N8O2

Mol. Mass.

436.5101

SMILES

[O-][N+](=O)c1ccccc1CC=CN=Nc1nc(nc(n1)N1CCCCC1)N1CCCCC1 |w:13.14,11.12|

Structure