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TargetDNA dC->dU-editing enzyme APOBEC-3A
LigandBDBM80546
Substrate/Competitorn/a
Meas. Tech.Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay
Temperature298.15±n/a K
IC50 1890±n/a nM
Commentsextracted
Citation PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
DNA dC->dU-editing enzyme APOBEC-3A
Name:DNA dC->dU-editing enzyme APOBEC-3A
Synonyms:ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A
Type:Enzyme Catalytic Domain
Mol. Mass.:23013.77
Organism:Homo sapiens (Human)
Description:gi_21955158
Residue:199
Sequence:
MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
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  Blast E-value cutoff:
BDBM80546
n/a
NameBDBM80546
Synonyms:1-{2-[(5-Dimethylsulfamoyl-furan-2-carbonyl)-amino]-ethyl}-1-methyl-azepanium | 5-(dimethylsulfamoyl)-N-[2-(1-methyl-1-azepan-1-iumyl)ethyl]-2-furancarboxamide;iodide | 5-(dimethylsulfamoyl)-N-[2-(1-methylazepan-1-ium-1-yl)ethyl]-2-furamide;iodide | 5-(dimethylsulfamoyl)-N-[2-(1-methylazepan-1-ium-1-yl)ethyl]furan-2-carboxamide;iodide | MLS001212477 | SMR000518608 | cid_24747087
TypeSmall organic molecule
Emp. Form.C16H28N3O4S
Mol. Mass.358.476
SMILESCN(C)S(=O)(=O)c1ccc(o1)C(=O)NCC[N+]1(C)CCCCCC1
Structure
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