| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
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| Ligand | BDBM61352 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 1550±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3A DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
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| BDBM61352 |
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| n/a |
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| Name | BDBM61352 |
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| Synonyms: | 5-methyl-6-oxo-3-benzo[b][1,4]benzothiazepinecarboxylic acid ethyl ester | 6-keto-5-methyl-benzo[b][1,4]benzothiazepine-3-carboxylic acid ethyl ester | MLS001200939 | SMR000564429 | cid_4068244 | ethyl 10-methyl-11-oxo-10,11-dihydrodibenzo[b,f][1,4]thiazepine-8-carboxylate | ethyl 5-methyl-6-oxidanylidene-benzo[b][1,4]benzothiazepine-3-carboxylate | ethyl 5-methyl-6-oxobenzo[b][1,4]benzothiazepine-3-carboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C17H15NO3S |
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| Mol. Mass. | 313.371 |
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| SMILES | CCOC(=O)c1ccc2Sc3ccccc3C(=O)N(C)c2c1 |
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| Structure | 
|
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