Ki Summary

Reaction Details

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Target

C-C chemokine receptor type 6

Ligand

BDBM48729

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay

IC50

3120±n/a nM

Citation

PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

C-C chemokine receptor type 6

Name:

C-C chemokine receptor type 6

Synonyms:

Type:

Enzyme

Mol. Mass.:

42510.84

Organism:

Homo sapiens (Human)

Description:

P51684

Residue:

374

Sequence:

MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM

BDBM48729

n/a

Name

BDBM48729

Synonyms:

4-Methyl-N-[4-oxo-3-(2H-[1,2,4]triazol-3-ylsulfanyl)-4H-naphthalen-1-ylidene]-benzenesulfonamide | 4-methyl-N-[4-oxidanylidene-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-ylidene]benzenesulfonamide | 4-methyl-N-[4-oxo-3-(1H-1,2,4-triazol-5-ylsulfanyl)naphthalen-1-ylidene]benzenesulfonamide | 4-methyl-N-[4-oxo-3-(1H-1,2,4-triazol-5-ylthio)-1-naphthalenylidene]benzenesulfonamide | MLS000554446 | N-[4-keto-3-(1H-1,2,4-triazol-5-ylthio)-1-naphthylidene]-4-methyl-benzenesulfonamide | SMR000171400 | cid_1015540

Type

Small organic molecule

Emp. Form.

C19H14N4O3S2

Mol. Mass.

410.469

SMILES

Cc1ccc(cc1)S(=O)(=O)N=C1C=C(Sc2nnc[nH]2)C(=O)c2ccccc12 |w:10.10,t:13|

Structure