Ki Summary

Reaction Details

Report a problem with these data

Target

C-C chemokine receptor type 6

Ligand

BDBM34855

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay

IC50

11100±n/a nM

Citation

PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

C-C chemokine receptor type 6

Name:

C-C chemokine receptor type 6

Synonyms:

Type:

Enzyme

Mol. Mass.:

42510.84

Organism:

Homo sapiens (Human)

Description:

P51684

Residue:

374

Sequence:

MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM

BDBM34855

n/a

Name

BDBM34855

Synonyms:

MLS000699314 | N,N'-bis(5-keto-6-methyl-3-thioxo-2H-1,2,4-triazin-4-yl)malonamide | N,N'-bis(6-methyl-5-oxidanylidene-3-sulfanylidene-2H-1,2,4-triazin-4-yl)propanediamide | N,N'-bis(6-methyl-5-oxo-3-sulfanylidene-2H-1,2,4-triazin-4-yl)propanediamide | N~1~,N~3~-bis(6-methyl-5-oxo-3-thioxo-2,5-dihydro-1,2,4-triazin-4(3H)-yl)malonamide | SMR000229794 | cid_9500339

Type

Small organic molecule

Emp. Form.

C11H12N8O4S2

Mol. Mass.

384.394

SMILES

Cc1n[nH]c(=S)n(NC(=O)CC(=O)Nn2c(=S)[nH]nc(C)c2=O)c1=O

Structure