| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 6 |
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| Ligand | BDBM72680 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay |
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| IC50 | 14900±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| C-C chemokine receptor type 6 |
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| Name: | C-C chemokine receptor type 6 |
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| Synonyms: | C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22 |
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| Type: | Enzyme |
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| Mol. Mass.: | 42510.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51684 |
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| Residue: | 374 |
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| Sequence: | MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM
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| BDBM72680 |
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| n/a |
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| Name | BDBM72680 |
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| Synonyms: | 5-[5-(4-Chloro-phenyl)-pyrazolidin-3-ylidene]-1,3-dimethyl-pyrimidine-2,4,6-trione | 5-[5-(4-chlorophenyl)-3-pyrazolidinylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione | 5-[5-(4-chlorophenyl)pyrazolidin-3-ylidene]-1,3-dimethyl-1,3-diazinane-2,4,6-trione | 5-[5-(4-chlorophenyl)pyrazolidin-3-ylidene]-1,3-dimethyl-barbituric acid | MLS000762999 | SMR000439471 | cid_6224486 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H15ClN4O3 |
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| Mol. Mass. | 334.758 |
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| SMILES | CN1C(=O)C(C2CC(N=N2)c2ccc(Cl)cc2)C(=O)N(C)C1=O |c:8| |
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| Structure | 
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