Reaction Details |
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Target | C-C chemokine receptor type 6 |
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Ligand | BDBM58116 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay |
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IC50 | 11700±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of small molecule antagonists of the CCR6 receptor: a luminescent beta-arrestin assay PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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C-C chemokine receptor type 6 |
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Name: | C-C chemokine receptor type 6 |
Synonyms: | C-C chemokine receptor type 6 | C-C chemokine receptor type 6 (CCR6) | CCR6 | CCR6_HUMAN | CKRL3 | CMKBR6 | GPR29 | STRL22 |
Type: | Enzyme |
Mol. Mass.: | 42510.84 |
Organism: | Homo sapiens (Human) |
Description: | P51684 |
Residue: | 374 |
Sequence: | MSGESMNFSDVFDSSEDYFVSVNTSYYSVDSEMLLCSLQEVRQFSRLFVPIAYSLICVFG
LLGNILVVITFAFYKKARSMTDVYLLNMAIADILFVLTLPFWAVSHATGAWVFSNATCKL
LKGIYAINFNCGMLLLTCISMDRYIAIVQATKSFRLRSRTLPRSKIICLVVWGLSVIISS
STFVFNQKYNTQGSDVCEPKYQTVSEPIRWKLLMLGLELLFGFFIPLMFMIFCYTFIVKT
LVQAQNSKRHKAIRVIIAVVLVFLACQIPHNMVLLVTAANLGKMNRSCQSEKLIGYTKTV
TEVLAFLHCCLNPVLYAFIGQKFRNYFLKILKDLWCVRRKYKSSGFSCAGRYSENISRQT
SETADNDNASSFTM
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BDBM58116 |
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n/a |
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Name | BDBM58116 |
Synonyms: | Heptanoic acid N'-[1-sec-butyl-4,6-dioxo-2-thioxo-tetrahydro-pyrimidin-(5E)-ylidenemethyl]-hydrazide | MLS000559859 | N'-[(E)-(1-butan-2-yl-4,6-dioxo-2-sulfanylidene-1,3-diazinan-5-ylidene)methyl]heptanehydrazide | N'-[(E)-(4,6-diketo-1-sec-butyl-2-thioxo-hexahydropyrimidin-5-ylidene)methyl]enanthohydrazide | N'-[(E)-[1-butan-2-yl-4,6-bis(oxidanylidene)-2-sulfanylidene-1,3-diazinan-5-ylidene]methyl]heptanehydrazide | SMR000439319 | cid_6376117 |
Type | Small organic molecule |
Emp. Form. | C16H26N4O3S |
Mol. Mass. | 354.468 |
SMILES | CCCCCCC(=O)NNC=C1C(=O)NC(=S)N(C(C)CC)C1=O |w:10.9| |
Structure |
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