| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Cysteine protease ATG4B |
|---|
| Ligand | BDBM43254 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. |
|---|
| IC50 | 1280±n/a nM |
|---|
| Citation |  PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Cysteine protease ATG4B |
|---|
| Name: | Cysteine protease ATG4B |
|---|
| Synonyms: | APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44279.79 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_47132611 |
|---|
| Residue: | 393 |
|---|
| Sequence: | MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA
CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
|
|
|
|---|
| BDBM43254 |
|---|
| n/a |
|---|
| Name | BDBM43254 |
|---|
| Synonyms: | (1Z)-1-[(benzylamino)methylene]-3-nitro-6,7,8,9-tetrahydrodibenzofuran-2-one | (1Z)-1-[(benzylamino)methylidene]-3-nitro-6,7,8,9-tetrahydrodibenzofuran-2-one | (1Z)-3-nitro-1-[[(phenylmethyl)amino]methylidene]-6,7,8,9-tetrahydrodibenzofuran-2-one | 1-[(E)-Benzylimino-methyl]-3-nitro-6,7,8,9-tetrahydro-dibenzofuran-2-ol | MLS000587848 | SMR000211848 | cid_6348160 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H18N2O4 |
|---|
| Mol. Mass. | 350.3679 |
|---|
| SMILES | [O-][N+](=O)c1cc2oc3CCCCc3c2[c-](\C=[NH+]\Cc2ccccc2)c1=O |
|---|
| Structure | 
|
|---|
Search and Browse
