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TargetCysteine protease ATG4B
LigandBDBM46229
Substrate/Competitorn/a
Meas. Tech.Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B.
IC50 6640±n/a nM
Citation PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Cysteine protease ATG4B
Name:Cysteine protease ATG4B
Synonyms:APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck
Type:Enzyme Catalytic Domain
Mol. Mass.:44279.79
Organism:Homo sapiens (Human)
Description:gi_47132611
Residue:393
Sequence:
MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA
CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM46229
n/a
NameBDBM46229
Synonyms:4-chloranyl-N-(3,4-dihydro-2H-thiochromen-4-yl)-3-sulfamoyl-benzamide | 4-chloro-3-sulfamoyl-N-thiochroman-4-yl-benzamide | 4-chloro-N-(3,4-dihydro-2H-1-benzothiopyran-4-yl)-3-sulfamoylbenzamide | 4-chloro-N-(3,4-dihydro-2H-thiochromen-4-yl)-3-sulfamoylbenzamide | MLS-0336143.0001 | cid_16330874
TypeSmall organic molecule
Emp. Form.C16H15ClN2O3S2
Mol. Mass.382.885
SMILESNS(=O)(=O)c1cc(ccc1Cl)C(=O)NC1CCSc2ccccc12
Structure
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