Reaction Details |
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Target | Cysteine protease ATG4B |
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Ligand | BDBM48038 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. |
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IC50 | 5850±n/a nM |
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Citation | PubChem, PC Dose response confirmation of the uHTS fluorescent assay for identification of inhibitors of ATG4B. PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Cysteine protease ATG4B |
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Name: | Cysteine protease ATG4B |
Synonyms: | APG4B | ATG4B | ATG4B_HUMAN | AUTL1 | KIAA0943 | cysteine protease ATG4B isoform a | hck |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 44279.79 |
Organism: | Homo sapiens (Human) |
Description: | gi_47132611 |
Residue: | 393 |
Sequence: | MDAATLTYDTLRFAEFEDFPETSEPVWILGRKYSIFTEKDEILSDVASRLWFTYRKNFPA
IGGTGPTSDTGWGCMLRCGQMIFAQALVCRHLGRDWRWTQRKRQPDSYFSVLNAFIDRKD
SYYSIHQIAQMGVGEGKSIGQWYGPNTVAQVLKKLAVFDTWSSLAVHIAMDNTVVMEEIR
RLCRTSVPCAGATAFPADSDRHCNGFPAGAEVTNRPSPWRPLVLLIPLRLGLTDINEAYV
ETLKHCFMMPQSLGVIGGKPNSAHYFIGYVGEELIYLDPHTTQPAVEPTDGCFIPDESFH
CQHPPCRMSIAELDPSIAVGFFCKTEDDFNDWCQQVKKLSLLGGALPMFELVELQPSHLA
CPDVLNLSLDSSDVERLERFFDSEDEDFEILSL
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BDBM48038 |
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n/a |
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Name | BDBM48038 |
Synonyms: | 4-[(E)-[3-(2-methylanilino)-4-oxo-1-naphthalenylidene]amino]sulfonylbenzoic acid | 4-[(E)-[3-(2-methylanilino)-4-oxonaphthalen-1-ylidene]amino]sulfonylbenzoic acid | 4-[(E)-[3-[(2-methylphenyl)amino]-4-oxidanylidene-naphthalen-1-ylidene]amino]sulfonylbenzoic acid | 4-[(E)-[4-keto-3-(o-toluidino)-1-naphthylidene]amino]sulfonylbenzoic acid | MLS000948152 | SMR000620455 | cid_6023693 |
Type | Small organic molecule |
Emp. Form. | C24H18N2O5S |
Mol. Mass. | 446.475 |
SMILES | Cc1ccccc1NC1=CC(=NS(=O)(=O)c2ccc(cc2)C(O)=O)c2ccccc2C1=O |w:11.12,t:9| |
Structure |
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