| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Hexokinase-1 |
|---|
| Ligand | BDBM80797 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay |
|---|
| EC50 | 46000±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Hexokinase-1 |
|---|
| Name: | Hexokinase-1 |
|---|
| Synonyms: | Brain form hexokinase | HK I | HK1 | HXK1_HUMAN | Hexokinase type I | Hexokinase-1 | hexokinase-1 isoform HKI |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 102488.34 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_11382 |
|---|
| Residue: | 917 |
|---|
| Sequence: | MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVH
GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGV
EGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT
KDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDD
IRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG
IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAA
VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLRTEASS
|
|
|
|---|
| BDBM80797 |
|---|
| n/a |
|---|
| Name | BDBM80797 |
|---|
| Synonyms: | (4-morpholinosulfonylphenyl)-[5-(1,2,5-trimethylpyrrol-3-yl)-6H-1,3,4-thiadiazin-2-yl]amine | MLS000761185 | N-(4-morpholin-4-ylsulfonylphenyl)-5-(1,2,5-trimethylpyrrol-3-yl)-6H-1,3,4-thiadiazin-2-amine | N-[4-(4-morpholinylsulfonyl)phenyl]-5-(1,2,5-trimethyl-3-pyrrolyl)-6H-1,3,4-thiadiazin-2-amine | SMR000365305 | cid_4882843 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H25N5O3S2 |
|---|
| Mol. Mass. | 447.574 |
|---|
| SMILES | Cc1cc(c(C)n1C)C1=NN=C(Nc2ccc(cc2)S(=O)(=O)N2CCOCC2)SC1 |t:9,11| |
|---|
| Structure | 
|
|---|
Search and Browse
