| Reaction Details |
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 | Report a problem with these data |
| Target | Hexokinase-1 |
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| Ligand | BDBM80804 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay |
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| EC50 | 21100±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of activators of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Hexokinase-1 |
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| Name: | Hexokinase-1 |
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| Synonyms: | Brain form hexokinase | HK I | HK1 | HXK1_HUMAN | Hexokinase type I | Hexokinase-1 | hexokinase-1 isoform HKI |
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| Type: | PROTEIN |
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| Mol. Mass.: | 102488.34 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_11382 |
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| Residue: | 917 |
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| Sequence: | MIAAQLLAYYFTELKDDQVKKIDKYLYAMRLSDETLIDIMTRFRKEMKNGLSRDFNPTAT
VKMLPTFVRSIPDGSEKGDFIALDLGGSSFRILRVQVNHEKNQNVHMESEVYDTPENIVH
GSGSQLFDHVAECLGDFMEKRKIKDKKLPVGFTFSFPCQQSKIDEAILITWTKRFKASGV
EGADVVKLLNKAIKKRGDYDANIVAVVNDTVGTMMTCGYDDQHCEVGLIIGTGTNACYME
ELRHIDLVEGDEGRMCINTEWGAFGDDGSLEDIRTEFDREIDRGSLNPGKQLFEKMVSGM
YLGELVRLILVKMAKEGLLFEGRITPELLTRGKFNTSDVSAIEKNKEGLHNAKEILTRLG
VEPSDDDCVSVQHVCTIVSFRSANLVAATLGAILNRLRDNKGTPRLRTTVGVDGSLYKTH
PQYSRRFHKTLRRLVPDSDVRFLLSESGSGKGAAMVTAVAYRLAEQHRQIEETLAHFHLT
KDMLLEVKKRMRAEMELGLRKQTHNNAVVKMLPSFVRRTPDGTENGDFLALDLGGTNFRV
LLVKIRSGKKRTVEMHNKIYAIPIEIMQGTGEELFDHIVSCISDFLDYMGIKGPRMPLGF
TFSFPCQQTSLDAGILITWTKGFKATDCVGHDVVTLLRDAIKRREEFDLDVVAVVNDTVG
TMMTCAYEEPTCEVGLIVGTGSNACYMEEMKNVEMVEGDQGQMCINMEWGAFGDNGCLDD
IRTHYDRLVDEYSLNAGKQRYEKMISGMYLGEIVRNILIDFTKKGFLFRGQISETLKTRG
IFETKFLSQIESDRLALLQVRAILQQLGLNSTCDDSILVKTVCGVVSRRAAQLCGAGMAA
VVDKIRENRGLDRLNVTVGVDGTLYKLHPHFSRIMHQTVKELSPKCNVSFLLSEDGSGKG
AALITAVGVRLRTEASS
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| BDBM80804 |
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| n/a |
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| Name | BDBM80804 |
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| Synonyms: | 2-Ethyl-3-methyl-1-methylamino-benzo[4,5]imidazo[1,2-a]pyridine-4-carbonitrile | 2-ethyl-3-methyl-1-(methylamino)-4-pyrido[1,2-a]benzimidazolecarbonitrile | 2-ethyl-3-methyl-1-(methylamino)pyrido[1,2-a]benzimidazole-4-carbonitrile | MLS001198575 | SMR000558985 | cid_779734 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H16N4 |
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| Mol. Mass. | 264.325 |
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| SMILES | CCc1c(C)c(C#N)c2nc3ccccc3n2c1NC |
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| Structure | 
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