| Reaction Details |
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 | Report a problem with these data |
| Target | Hexokinase HKDC1 [W721R] |
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| Ligand | BDBM75323 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay |
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| IC50 | 80000±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Hexokinase HKDC1 [W721R] |
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| Name: | Hexokinase HKDC1 [W721R] |
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| Synonyms: | HKDC1 | HKDC1_HUMAN | putative hexokinase HKDC1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 102520.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_156151420 |
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| Residue: | 917 |
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| Sequence: | MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
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| BDBM75323 |
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| n/a |
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| Name | BDBM75323 |
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| Synonyms: | 2-[4-[[[4-[2-(4-chloroanilino)-1,3-thiazol-4-yl]benzoyl]hydrazinylidene]methyl]phenoxy]acetic acid | 2-[4-[[[4-[2-(4-chloroanilino)thiazol-4-yl]benzoyl]hydrazono]methyl]phenoxy]acetic acid | 2-[4-[[[4-[2-[(4-chlorophenyl)amino]-1,3-thiazol-4-yl]phenyl]carbonylhydrazinylidene]methyl]phenoxy]ethanoic acid | 2-[4-[[[[4-[2-(4-chloroanilino)-4-thiazolyl]phenyl]-oxomethyl]hydrazinylidene]methyl]phenoxy]acetic acid | MLS000703184 | SMR000273648 | cid_3143384 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H19ClN4O4S |
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| Mol. Mass. | 506.961 |
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| SMILES | OC(=O)COc1ccc(C=NNC(=O)c2ccc(cc2)-c2csc(Nc3ccc(Cl)cc3)n2)cc1 |
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| Structure | 
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