| Reaction Details |
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 | Report a problem with these data |
| Target | Hexokinase HKDC1 [W721R] |
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| Ligand | BDBM48027 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay |
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| IC50 | 27300±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Hexokinase HKDC1 [W721R] |
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| Name: | Hexokinase HKDC1 [W721R] |
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| Synonyms: | HKDC1 | HKDC1_HUMAN | putative hexokinase HKDC1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 102520.24 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_156151420 |
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| Residue: | 917 |
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| Sequence: | MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
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| BDBM48027 |
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| n/a |
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| Name | BDBM48027 |
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| Synonyms: | 4-[[(4E)-1-keto-4-mesitylsulfonylimino-2-naphthyl]amino]benzoic acid | 4-[[(4E)-1-oxidanylidene-4-(2,4,6-trimethylphenyl)sulfonylimino-naphthalen-2-yl]amino]benzoic acid | 4-[[(4E)-1-oxo-4-(2,4,6-trimethylphenyl)sulfonylimino-2-naphthalenyl]amino]benzoic acid | 4-[[(4E)-1-oxo-4-(2,4,6-trimethylphenyl)sulfonyliminonaphthalen-2-yl]amino]benzoic acid | MLS000948031 | SMR000620244 | cid_9609431 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H22N2O5S |
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| Mol. Mass. | 474.528 |
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| SMILES | Cc1cc(C)c(c(C)c1)S(=O)(=O)N=C1C=C(Nc2ccc(cc2)C(O)=O)C(=O)c2ccccc12 |w:12.12,t:15| |
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| Structure | 
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