| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Hexokinase HKDC1 [W721R] |
|---|
| Ligand | BDBM48038 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay |
|---|
| IC50 | 2840±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of inhibitors of hexokinase domain containing I (HKDC1) in the hexokinase 1 selectivity assay PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Hexokinase HKDC1 [W721R] |
|---|
| Name: | Hexokinase HKDC1 [W721R] |
|---|
| Synonyms: | HKDC1 | HKDC1_HUMAN | putative hexokinase HKDC1 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 102520.24 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_156151420 |
|---|
| Residue: | 917 |
|---|
| Sequence: | MFAVHLMAFYFSKLKEDQIKKVDRFLYHMRLSDDTLLDIMRRFRAEMEKGLAKDTNPTAA
VKMLPTFVRAIPDGSENGEFLSLDLGGSKFRVLKVQVAEEGKRHVQMESQFYPTPNEIIR
GNGTELFEYVADCLADFMKTKDLKHKKLPLGLTFSFPCRQTKLEEGVLLSWTKKFKARGV
QDTDVVSRLTKAMRRHKDMDVDILALVNDTVGTMMTCAYDDPYCEVGVIIGTGTNACYME
DMSNIDLVEGDEGRMCINTEWGAFGDDGALEDIRTEFDRELDLGSLNPGKQLFEKMISGL
YLGELVRLILLKMAKAGLLFGGEKSSALHTKGKIETRHVAAMEKYKEGLANTREILVDLG
LEPSEADCIAVQHVCTIVSFRSANLCAAALAAILTRLRENKKVERLRTTVGMDGTLYKIH
PQYPKRLHKVVRKLVPSCDVRFLLSESGSTKGAAMVTAVASRVQAQRKQIDRVLALFQLT
REQLVDVQAKMRAELEYGLKKKSHGLATVRMLPTYVCGLPDGTEKGKFLALDLGGTNFRV
LLVKIRSGRRSVRMYNKIFAIPLEIMQGTGEELFDHIVQCIADFLDYMGLKGASLPLGFT
FSFPCRQMSIDKGTLIGWTKGFKATDCEGEDVVDMLREAIKRRNEFDLDIVAVVNDTVGT
MMTCGYEDPNCEIGLIAGTGSNMCYMEDMRNIEMVEGGEGKMCINTEWGGFGDNGCIDDI
RTRYDTEVDEGSLNPGKQRYEKMTSGMYLGEIVRQILIDLTKQGLLFRGQISERLRTRGI
FETKFLSQIESDRLALLQVRRILQQLGLDSTCEDSIVVKEVCGAVSRRAAQLCGAGLAAI
VEKRREDQGLEHLRITVGVDGTLYKLHPHFSRILQETVKELAPRCDVTFMLSEDGSGKGA
ALITAVAKRLQQAQKEN
|
|
|
|---|
| BDBM48038 |
|---|
| n/a |
|---|
| Name | BDBM48038 |
|---|
| Synonyms: | 4-[(E)-[3-(2-methylanilino)-4-oxo-1-naphthalenylidene]amino]sulfonylbenzoic acid | 4-[(E)-[3-(2-methylanilino)-4-oxonaphthalen-1-ylidene]amino]sulfonylbenzoic acid | 4-[(E)-[3-[(2-methylphenyl)amino]-4-oxidanylidene-naphthalen-1-ylidene]amino]sulfonylbenzoic acid | 4-[(E)-[4-keto-3-(o-toluidino)-1-naphthylidene]amino]sulfonylbenzoic acid | MLS000948152 | SMR000620455 | cid_6023693 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C24H18N2O5S |
|---|
| Mol. Mass. | 446.475 |
|---|
| SMILES | Cc1ccccc1NC1=CC(=NS(=O)(=O)c2ccc(cc2)C(O)=O)c2ccccc2C1=O |w:11.12,t:9| |
|---|
| Structure | 
|
|---|
Search and Browse
