| Reaction Details |
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 | Report a problem with these data |
| Target | Methionine aminopeptidase 2 |
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| Ligand | BDBM81355 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Enzyme Inhibiton Assay |
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| IC50 | >5.00e+5±n/a nM |
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| Citation |  Chen, X; Xie, S; Bhat, S; Kumar, N; Shapiro, TA; Liu, JO Fumagillin and fumarranol interact with P. falciparum methionine aminopeptidase 2 and inhibit malaria parasite growth in vitro and in vivo. Chem Biol16:193-202 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Methionine aminopeptidase 2 |
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| Name: | Methionine aminopeptidase 2 |
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| Synonyms: | MetAP2 | Methionine aminopeptidase (MetAP2) |
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| Type: | Protein |
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| Mol. Mass.: | 40537.47 |
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| Organism: | Plasmodium falciparum |
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| Description: | Q8TA23 |
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| Residue: | 354 |
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| Sequence: | MIYGKDGKYPVGEILEYNNYNLSGQSLVEKKEREKLSIDYYEDLRKAAECHRQVRKHMQA
FIKPGKKMIDIAQETERKTKELILAEKLKCGWGFPTGCSLNHCAAHYTPNYGDETVLKYD
DVCKLDFGVHVNGYIIDCAFTIAFNEKYDNLIKATQDGTNTGIKEAGIDARMCDIGEAIQ
EAIESYEIELNQKIYPIKAISNLRGHSINKYIIHGGKCVPIVRQKEKNEIMEEGELFAIE
TFASTGKGYVNHENECSHYMRNPEKQFVPIRLNSAKTLLKVINDNFDTLPFCNRWLDDLG
QTRHFMALKTLIDLNIVEPYPPLCDIKNSFTSQMEHTILLRPTCKEVLSRGPDF
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| BDBM81355 |
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| n/a |
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| Name | BDBM81355 |
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| Synonyms: | Fumarranol Analog, 10 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H26O4 |
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| Mol. Mass. | 282.3752 |
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| SMILES | [#6]-[#8][C@@]12[#6]([C@@]3([#6])[#8]-[#6@@H]3-[#6]\[#6]=[#6](\[#6])-[#6])[C@]1([#6]-[#8])[#6]-[#6]-[#6@H]2-[#8] |r| |
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| Structure | 
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