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TargetDipeptidyl peptidase 1
LigandBDBM81406
Substrate/Competitorn/a
Meas. Tech.Fluorogenic Assay
IC50 700±0.0 nM
Citation Deu, ELeyva, MJAlbrow, VERice, MJEllman, JABogyo, M Functional studies of Plasmodium falciparum dipeptidyl aminopeptidase I using small molecule inhibitors and active site probes. Chem Biol17:808-19 (2010) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Dipeptidyl peptidase 1
Name:Dipeptidyl peptidase 1
Synonyms:CATC_MOUSE | Ctsc | Dipeptidyl peptidase I
Type:PROTEIN
Mol. Mass.:52379.83
Organism:Mus musculus
Description:ChEMBL_44964
Residue:462
Sequence:
MGPWTHSLRAVLLLVLLGVCTVRSDTPANCTYPDLLGTWVFQVGPRSSRSDINCSVMEAT
EEKVVVHLKKLDTAYDELGNSGHFTLIYNQGFEIVLNDYKWFAFFKYEVRGHTAISYCHE
TMTGWVHDVLGRNWACFVGKKVESHIEKVNMNAAHLGGLQERYSERLYTHNHNFVKAINT
VQKSWTATAYKEYEKMSLRDLIRRSGHSQRIPRPKPAPMTDEIQQQILNLPESWDWRNVQ
GVNYVSPVRNQESCGSCYSFASMGMLEARIRILTNNSQTPILSPQEVVSCSPYAQGCDGG
FPYLIAGKYAQDFGVVEESCFPYTAKDSPCKPRENCLRYYSSDYYYVGGFYGGCNEALMK
LELVKHGPMAVAFEVHDDFLHYHSGIYHHTGLSDPFNPFELTNHAVLLVGYGRDPVTGIE
YWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPIPKL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM81406
n/a
NameBDBM81406
Synonyms:ML4124
TypeSmall organic molecule
Emp. Form.C22H30F4N4O2
Mol. Mass.458.4928
SMILESCCCCC(C(=O)COc1c(F)c(F)cc(F)c1F)n1cc(nn1)C(N)(CCC)CCC |w:4.3|
Structure
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