| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 1 |
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| Ligand | BDBM81512 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorogenic Assay |
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| pH | 8±0 |
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| Temperature | 310.15±0 K |
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| IC50 | 3.25e+4± 2.8e+3 nM |
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| Citation |  Albrow, VE; Ponder, EL; Fasci, D; Békés, M; Deu, E; Salvesen, GS; Bogyo, M Development of small molecule inhibitors and probes of human SUMO deconjugating proteases. Chem Biol18:722-32 (2011) [PubMed] Article |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sentrin-specific protease 1 |
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| Name: | Sentrin-specific protease 1 |
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| Synonyms: | SENP1 | SENP1_HUMAN | Sentrin-specific protease 1 (SENP1) |
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| Type: | Protein |
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| Mol. Mass.: | 73500.42 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9P0U3 |
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| Residue: | 644 |
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| Sequence: | MDDIADRMRMDAGEVTLVNHNSVFKTHLLPQTGFPEDQLSLSDQQILSSRQGHLDRSFTC
STRSAAYNPSYYSDNPSSDSFLGSGDLRTFGQSANGQWRNSTPSSSSSLQKSRNSRSLYL
ETRKTSSGLSNSFAGKSNHHCHVSAYEKSFPIKPVPSPSWSGSCRRSLLSPKKTQRRHVS
TAEETVQEEEREIYRQLLQMVTGKQFTIAKPTTHFPLHLSRCLSSSKNTLKDSLFKNGNS
CASQIIGSDTSSSGSASILTNQEQLSHSVYSLSSYTPDVAFGSKDSGTLHHPHHHHSVPH
QPDNLAASNTQSEGSDSVILLKVKDSQTPTPSSTFFQAELWIKELTSVYDSRARERLRQI
EEQKALALQLQNQRLQEREHSVHDSVELHLRVPLEKEIPVTVVQETQKKGHKLTDSEDEF
PEITEEMEKEIKNVFRNGNQDEVLSEAFRLTITRKDIQTLNHLNWLNDEIINFYMNMLME
RSKEKGLPSVHAFNTFFFTKLKTAGYQAVKRWTKKVDVFSVDILLVPIHLGVHWCLAVVD
FRKKNITYYDSMGGINNEACRILLQYLKQESIDKKRKEFDTNGWQLFSKKSQEIPQQMNG
SDCGMFACKYADCITKDRPINFTQQHMPYFRKRMVWEILHRKLL
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| BDBM81512 |
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| n/a |
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| Name | BDBM81512 |
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| Synonyms: | VEA-417 |
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| Type | Small organic molecule |
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| Emp. Form. | C36H31N5O6 |
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| Mol. Mass. | 629.6612 |
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| SMILES | NC(=O)CNC(=O)c1ccc(cc1)C(=O)NNC(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12 |r| |
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| Structure | 
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