| Reaction Details |
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 | Report a problem with these data |
| Target | Histamine H2 receptor |
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| Ligand | BDBM22904 |
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| Substrate/Competitor | n/a |
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| Ki | 1±n/a nM |
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| Comments | PDSP_272 |
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| Citation |  Hill, SJ Multiple histamine receptors: properties and functional characteristics. Biochem Soc Trans20:122-5 (1992) [PubMed] Article |
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| More Info.: | Get all data from this article |
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| Histamine H2 receptor |
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| Name: | Histamine H2 receptor |
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| Synonyms: | Gastric receptor I | H2R | HISTAMINE H2 | HRH2 | HRH2_CAVPO | Histamine H2-Gs alpha S |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40567.22 |
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| Organism: | Cavia porcellus (domestic guinea pig) |
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| Description: | For the H2 receptor-binding assays, guinea pig striatum was used. |
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| Residue: | 359 |
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| Sequence: | MAFNGTVPSFCMDFTVYKVTISVILIILILVTVAGNVVVCLAVGLNRRLRSLTNCFIVSL
AVTDLLLGLLVLPFSAIYQLSCKWSFSKVFCNIYTSLDVMLCTASILNLFMISLDRYCAV
TDPLRYPVLITPARVAISLVFIWVISITLSFLSIHLGWNSRNETSKDNDTIVKCKVQVNE
VYGLVDGLVTFYLPLLIMCITYFRIFKIAREQARRINHIGSWKAATIREHKATVTLAAVM
GAFIICWFPYFTVFVYRGLKGDDAVNEVFEDVVLWLGYANSALNPILYAALNRDFRTAYH
QLFCCRLASHNSHETSLRLNNSQLNRSQCQEPRWQEDKPLNLQVWSGTEVTAPQGATNR
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| BDBM22904 |
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| n/a |
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| Name | BDBM22904 |
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| Synonyms: | (2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alpha-Methylhistamine | Alpha-Methylhistamine-R | Alpha-Methylhistane-R | CHEMBL268229 | R-alpha-methylhistamine | RAMH |
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| Type | Small organic molecule |
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| Emp. Form. | C6H11N3 |
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| Mol. Mass. | 125.1716 |
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| SMILES | C[C@@H](N)Cc1cnc[nH]1 |r| |
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| Structure | 
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