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Targetp53 binding protein
LigandBDBM81635
Substrate/Competitorn/a
Meas. Tech.HDM2 Binding Assay
IC50 1.7e+3±n/a nM
Citation Cummings, MDSchubert, CParks, DJCalvo, RRLaFrance, LVLattanze, JMilkiewicz, KLLu, T Substituted 1,4-benzodiazepine-2,5-diones as alpha-helix mimetic antagonists of the HDM2-p53 protein-protein interaction. Chem Biol Drug Des67:201-5 (2006) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
p53 binding protein
Name:p53 binding protein
Synonyms:HDM2 | HDM2-HD1 protein | HDM2-p53 protein | P53 binding protein
Type:Protein
Mol. Mass.:10726.49
Organism:Homo sapiens (Human)
Description:Q9H4C2
Residue:98
Sequence:
MCNTNMSVPTDGAVTTSQIPASEQETQDKEESVESSLPLNAIEPCVICQGRPKNGCIVHG
KTGHLMACFTCAKKLKKRNKPCPVCRQPIQMIVLTYFP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM81635
n/a
NameBDBM81635
Synonyms:BZD Scaffold, 5
TypeSmall organic molecule
Emp. Form.C23H15ClIN2O4
Mol. Mass.545.734
SMILES[O-]C(=O)C(N1C(c2ccc(Cl)cc2)C(=O)Nc2ccc(I)cc2C1=O)c1ccccc1
Structure
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