| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M3 |
|---|
| Ligand | BDBM50015720 |
|---|
| Substrate/Competitor | n/a |
|---|
| Ki | 0.44±n/a nM |
|---|
| Comments | PDSP_1688 |
|---|
| Citation |  Bolden, C; Cusack, B; Richelson, E Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells. J Pharmacol Exp Ther260:576-80 (1992) [PubMed] |
|---|
| More Info.: | Get all data from this article |
|---|
| |
| Muscarinic acetylcholine receptor M3 |
|---|
| Name: | Muscarinic acetylcholine receptor M3 |
|---|
| Synonyms: | ACM3_HUMAN | CHRM3 | Cholinergic, muscarinic M3 | Muscarinic Receptors M3 | Muscarinic receptor M3 | RecName: Full=Muscarinic acetylcholine receptor M3 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 66151.03 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P20309 |
|---|
| Residue: | 590 |
|---|
| Sequence: | MTLHNNSTTSPLFPNISSSWIHSPSDAGLPPGTVTHFGSYNVSRAAGNFSSPDGTTDDPL
GGHTVWQVVFIAFLTGILALVTIIGNILVIVSFKVNKQLKTVNNYFLLSLACADLIIGVI
SMNLFTTYIIMNRWALGNLACDLWLAIDYVASNASVMNLLVISFDRYFSITRPLTYRAKR
TTKRAGVMIGLAWVISFVLWAPAILFWQYFVGKRTVPPGECFIQFLSEPTITFGTAIAAF
YMPVTIMTILYWRIYKETEKRTKELAGLQASGTEAETENFVHPTGSSRSCSSYELQQQSM
KRSNRRKYGRCHFWFTTKSWKPSSEQMDQDHSSSDSWNNNDAAASLENSASSDEEDIGSE
TRAIYSIVLKLPGHSTILNSTKLPSSDNLQVPEEELGMVDLERKADKLQAQKSVDDGGSF
PKSFSKLPIQLESAVDTAKTSDVNSSVGKSTATLPLSFKEATLAKRFALKTRSQITKRKR
MSLVKEKKAAQTLSAILLAFIITWTPYNIMVLVNTFCDSCIPKTFWNLGYWLCYINSTVN
PVCYALCNKTFRTTFKMLLLCQCDKKKRRKQQYQQRQSVIFHKRAPEQAL
|
|
|
|---|
| BDBM50015720 |
|---|
| n/a |
|---|
| Name | BDBM50015720 |
|---|
| Synonyms: | (hyoscine)3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester | 3-hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester | 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl 3-hydroxy-2-phenylpropanoate | Benzotropine3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester | CHEMBL13030 | ChEMBL_11434 | SCOPOLAMINE |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H21NO4 |
|---|
| Mol. Mass. | 303.3529 |
|---|
| SMILES | CN1C2CC(CC1C1OC21)OC(=O)C(CO)c1ccccc1 |TLB:8:9:1:3.5.4,8:7:1:3.5.4,0:1:9.7:3.5.4,THB:10:4:9.7:1| |
|---|
| Structure | 
|
|---|
Search and Browse
