| Reaction Details |
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 | Report a problem with these data |
| Target | Muscarinic acetylcholine receptor M5 |
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| Ligand | BDBM35255 |
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| Substrate/Competitor | n/a |
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| Ki | 260±n/a nM |
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| Comments | PDSP_2002 |
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| Citation |  Bolden, C; Cusack, B; Richelson, E Antagonism by antimuscarinic and neuroleptic compounds at the five cloned human muscarinic cholinergic receptors expressed in Chinese hamster ovary cells. J Pharmacol Exp Ther260:576-80 (1992) [PubMed] |
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| More Info.: | Get all data from this article |
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| Muscarinic acetylcholine receptor M5 |
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| Name: | Muscarinic acetylcholine receptor M5 |
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| Synonyms: | ACM5_HUMAN | CHRM5 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 60102.35 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1517990 |
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| Residue: | 532 |
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| Sequence: | MEGDSYHNATTVNGTPVNHQPLERHRLWEVITIAAVTAVVSLITIVGNVLVMISFKVNSQ
LKTVNNYYLLSLACADLIIGIFSMNLYTTYILMGRWALGSLACDLWLALDYVASNASVMN
LLVISFDRYFSITRPLTYRAKRTPKRAGIMIGLAWLISFILWAPAILCWQYLVGKRTVPL
DECQIQFLSEPTITFGTAIAAFYIPVSVMTILYCRIYRETEKRTKDLADLQGSDSVTKAE
KRKPAHRALFRSCLRCPRPTLAQRERNQASWSSSRRSTSTTGKPSQATGPSANWAKAEQL
TTCSSYPSSEDEDKPATDPVLQVVYKSQGKESPGEEFSAEETEETFVKAETEKSDYDTPN
YLLSPAAAHRPKSQKCVAYKFRLVVKADGNQETNNGCHKVKIMPCPFPVAKEPSTKGLNP
NPSHQMTKRKRVVLVKERKAAQTLSAILLAFIITWTPYNIMVLVSTFCDKCVPVTLWHLG
YWLCYVNSTVNPICYALCNRTFRKTFKMLLLCRWKKKKVEEKLYWQGNSKLP
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| BDBM35255 |
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| n/a |
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| Name | BDBM35255 |
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| Synonyms: | 2-Chlor-11-(2-dimethylaminoaethoxy)-dibenzo(b,f)-thiepin | 2-Chloro-11-(2-(dimethylamino)ethoxy)dibenzo(b,f)thiepin | 2-[(8-chlorodibenzo[b,f]thiepin-10-yl)oxy]-N,N-dimethylethanamine | CHEMBL285802 | Nipolept | Zoleptil | zotepine |
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| Type | Small organic molecule |
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| Emp. Form. | C18H18ClNOS |
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| Mol. Mass. | 331.86 |
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| SMILES | CN(C)CCOC1=Cc2ccccc2Sc2ccc(Cl)cc12 |t:6| |
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| Structure | 
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